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Bioinformatik-Seminar für Humanbiologen

Inhalt

Zielsetzung des Seminars ist es, aktuelle Literatur aus dem Gebiet der Bioinformatik zu erarbeiten und kritisch zu diskutieren. Dazu erhalten die Studenten jeweils ein Paper, zu dem ein ca 3-seitiges Expose ausgearbeitet werden soll und das anschließend in einem Kurzvortrag (15 min.) vorgestellt werden soll.

Termine:

Achtung: Der ursprüglich geplante Termin am 12.6. ist wegen der Vollversammlung der Studierendenschaft leider nicht möglich!

Paper:

TitelAutorLinkBetreuer
Highly parallel direct RNA sequencing on an array of nanopores.Garalde et al. Nature Methods Neetika Nath
Can machine-learning improve cardiovascular risk prediction using routine clinical data?Weng et al. PLoS OneNeetika Naath
Identification of novel diagnostic biomarkers for thyroid carcinoma.Wang et al. Oncotarget Neetika Nath
Basic local alignment search tool. Altschul et al. ScienceDirect Stefan Neumann
Dynamics and heterogeneity of brain damage in multiple sclerosis Kotelnikova et al. Plos Comp Biol Stefan Neumann
Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses Lauber et al. Cell Host Microbe Stefan Neumann
Unexpected cross-species contamination in genome sequencing projects Merchant et al. PeerJ Stefan Neumann
Combining multi-dimensional data to identify key genes and pathways in gastric cancer Ren et al. PeerJ Marcus Vollmer
Detection of stable community structures within gut microbiota co-occurrence networks from different human populations Jackson et al. PeerJ Marcus Vollmer
Genome-wide identification and characterization of Dof transcription factors in eggplant (Solanum melongena L.) Wei et al. PeerJ Marcus Vollmer
BLAT - The BLAST-Like Alignment Tool Kent Genome Research Marcus Vollmer
Dynamic networks reveal key players in agingFaisal, MilenkovicBioinformaticsAnn-Kristin Becker
Predicting the sequence specifities of DNA- and RNA-binding proteins by deep learningAlipanahi et al.Nature Biotechnology Ann-Kristin Becker
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesSubramanian et al.PNASDarius Schweinoch
A novel signaling pathway impact analysisTarca et al.BioinformaticsDarius Schweinoch
I-TASSER: a unified platform for automated protein structure and function predictionRoy et al.Nature ProtocolsDarius Schweinoch
Similarity network fusion for aggregating data types on a genomic scaleWang et al.Nature MethodsOlliver Müller-Stricker
Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGMVaske et al.BioinformaticsOlliver Müller-Stricker
Gene prioritization through genomic data fusionAerts et al.Nature BiotechnologyOlliver Müller-Stricker
Detecting critical state before phase transition of complex biological systems by hidden Markov modelChen et al.BioinformaticsAnn-Kristin Becker
Stochastic gene expression in a single cell Elowitz, M et al. Science Arnab Bandyopadhyay
A synthetic oscillatory network of transcriptional regulators Elowitz, M et al. Nature Arnab Bandyopadhyay
A General Method for Numerically Simulating the Stochastic Time Evolution of Coupled Chemical Reactions Daniel T Gillespie J Comput Phys Arnab Bandyopadhyay